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MYP_062214
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Basic Information
Lactoperoxidase (LPO) (EC 1.11.1.7) (Salivary peroxidase) (SPO)
Antimicrobial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Enzyme / Catalytic activity ▸ Oxidoreductase
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
712 amino acids
C3586H5612N1000O1037S30
Standard
Sequence
MRVLLHLPALLASLILLQAAASTTRAQTTRTSAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKASLTNVTDPSLDLTSLSLEVGCGAPAPVVRCDPCSPYRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKPSPCEFINTTARVPCFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLGDHMQKWIPPYQGYSESVDPRISNVFTFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPWASVKN
Physicochemical Analysis
80286.95 Da
8.89
12.56
11.28
0.0176
-0.38
0.90
-0.03
40.30
80.86
0.0927
105310.00
106310.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0121786 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Peroxidase; XPO subfamily
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Oxidoreductase Peroxidase Non-hemolytic
Burkholderia cepacia (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8964511;19059195;16625196;15489334;2222811;10715594;12626341;16740002;18780401 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8964511/
RECORD: Rec_0208402 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Peroxidase; XPO subfamily
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Oxidoreductase Peroxidase Non-hemolytic
Haemophilus influenzae (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8964511;19059195;16625196;15489334;2222811;10715594;12626341;16740002;18780401 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8964511/
RECORD: Rec_0253571 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Peroxidase; XPO subfamily
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Oxidoreductase Peroxidase Non-hemolytic
Pseudomonas aeruginosa (Gram-negative)
PaperThe status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC) PMID8964511;19059195;16625196;15489334;2222811;10715594;12626341;16740002;18780401 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8964511/