Peptide Database

Peptide NameGallinacin-8 (Gal 8) (Beta-defensin 8) (Gallinacin-12) (Gal-12)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC323H514N94O89S8

DescriptionStandard

        MKILYLLLAVLLTVLQSSLGFMRVPNNEAQCEQAGGICSKDHCFHLHTRAFGHCQRGVPCCRTVYD
    

Molecular Weight7394.63 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.80

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0272

GRAVY Index0.19

Hydrophobic Moment 0.66

Boman Index0.10

Instability Index30.78

Aliphatic Index 93.03

Aromaticity 0.0758

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2921.18

LogP -27.56

H-bond Donors 107.0

H-bond Acceptors 103.0

Rotatable Bonds 242.0

Heavy Atoms 514.0

Ring Count 11.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0199158 VERIFIED: YES

Provenance & Taxonomy

OrganismGallus gallus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9031

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic