‹ ›
MYP_062154
← PREVIOUS NEXT → BACK
Basic Information
CL58+6
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
24 amino acids
C119H187N27O28S
Standard
Sequence
MANAGLQLLGFILAFLGWIGAIVS
Physicochemical Analysis
2475.99 Da
5.28
-0.50
-0.72
-0.0208
1.71
0.34
0.71
34.40
158.75
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
854.82
-2.73
29.0
29.0
79.0
175.0
4.0
25.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0220998 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Claudin-derived
9606;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor
Hepatitis C virus (Virus entry); Huh7.5.1
5.1 μM
Pseudoviral particle infection assay
PaperA human claudin-1-derived peptide inhibits hepatitis C virus entry. | Si Y, Liu S, Liu X, Jacobs JL, Cheng M, Niu Y, Jin Q, Wang T, Yang W. | Hepatology. 2012 | PMID:22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0256780 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Hepatitis C virus (HCV) PsV
PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0389522 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
FIRST PREV 1 2
Showing 3 records on this page · Page 2 of 2