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MYP_062154
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Basic Information
CL58+6
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Standard
24 amino acids
C119H187N27O28S
Standard
Sequence
MANAGLQLLGFILAFLGWIGAIVS
Physicochemical Analysis
2475.99 Da
5.28
-0.50
-0.72
-0.0208
1.71
0.34
0.71
34.40
158.75
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
854.82
-2.73
29.0
29.0
79.0
175.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051521 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
Hepatitis C virus (HCV) | Huh7.5.1 cells
5.1±0.6 μM
IC50
Mammalian: 30 h; Yeast: >20 h; E. coli: >10 h
PaperA human claudin-1-derived peptide inhibits hepatitis C virus entry. | Si Y, Liu S, Liu X, Jacobs JL, Cheng M, Niu Y, Jin Q, Wang T, Yang W. | Hepatology. 2012 Aug;56(2):507-15. | DOI:10.1002/hep.25685 | PMID:22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0060240 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0103224 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
cells
5.1±0.6 μM
IC50
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0149640 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Hepatitis C virus(HCV):inhibition of viral-entry in Huh7
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
RECORD: Rec_0171399 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
5
PaperPubMed PMID: 22378192 PMID22378192 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22378192/
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