Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC425H678N122O123S14

DescriptionStandard

        MKAFSIAVAVTLVLAFICILESSASPFTGVQELEEAGANDTPVAVYQGMSMESRMMPNHIRQKRQSHLSLCRWCCNCCKGNKGCGFCCRF
    

Molecular Weight9913.58 Da

Isoelectric Point (pI)8.43

Net Charge (pH 7.0)2.60

Net Charge (pH 7.4) 2.13

Charge Density (pH 7.0) 0.0288

GRAVY Index0.17

Hydrophobic Moment 0.57

Boman Index0.08

Instability Index63.13

Aliphatic Index 71.56

Aromaticity 0.0778

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3924.86

LogP -42.36

H-bond Donors 145.0

H-bond Acceptors 142.0

Rotatable Bonds 328.0

Heavy Atoms 684.0

Ring Count 13.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0044518 VERIFIED: NO

Provenance & Taxonomy

OrganismNotothenia angustata [Animal]

FamilyHepcidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0065215 VERIFIED: NO