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MYP_062142
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Basic Information
Thusin (ThsA1, ThsA2; a two-chain lantibiotic, type 2, class 1 bacteriocins)
Antimicrobial
Antimicrobial ▸ Antibacterial
Standard
38 amino acids
C175H281N49O60S3
Standard
Sequence
INTWNTTATSTSIIISETFGNKGKVCTYTVECVNNCRG
Physicochemical Analysis
4127.59 Da
7.94
0.73
0.48
0.0193
-0.14
0.40
0.06
23.10
66.58
0.0789
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1802.56
-25.24
67.0
64.0
134.0
287.0
4.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0357622 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Lantibiotic
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
pneumoniae ATCC 49619
PaperPubMed PMID: 27486447 PMID27486447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27486447/
RECORD: Rec_0366297 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Lantibiotic
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
amyloliquefaciens X1
12.5 μM
MIC
PaperPubMed PMID: 27486447 PMID27486447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27486447/
RECORD: Rec_0382521 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis strain [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus CMCC 26003, MRSA
25 μM
MIC
PaperThusin, a Novel Two-Component Lantibiotic with Potent Antimicrobial Activity against Several Gram-Positive Pathogens.
RECORD: Rec_0404106 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Lantibiotic
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
MRSA
25 μM
MIC
PaperPubMed PMID: 27486447 PMID27486447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27486447/
RECORD: Rec_0405211 VERIFIED: YES
Provenance & Taxonomy
Bacillus thuringiensis [Bacterium]
Lantibiotic
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 27486447 PMID27486447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27486447/
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