Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length166 amino acids

Chemical FormulaC804H1276N244O242S8

DescriptionStandard

        MYRSASSNRRKEQSSMAKVQFTKRQETSQIFVHCSATKAAMDIGVREIRQWHKEQGWLDVGYHFIIRRDGTVETGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGQPEANFTPQQMSALKGLLHELKGTYPKAVIMAHHDVAPKACPSFDLQRWVRTGELVTSDRG
    

Molecular Weight18488.74 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)6.10

Net Charge (pH 7.4) 5.44

Charge Density (pH 7.0) 0.0367

GRAVY Index-0.55

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index50.47

Aliphatic Index 67.53

Aromaticity 0.0723

Extinction Coeff. Reduced 22460.00

Extinction Coeff. Oxidized 22585.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7881.59

LogP -88.96

H-bond Donors 280.0

H-bond Acceptors 263.0

Rotatable Bonds 622.0

Heavy Atoms 1298.0

Ring Count 27.0

Amide Bonds 179.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0374746 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage Henu1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic