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MYP_062015
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Basic Information
Phenol-soluble modulin alpha 4 peptide (4-20), PSMalpha4 (4-20)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Immunomodulation ▸ Immunosuppressive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
17 amino acids
C90H158N20O21
Standard
Sequence
VGTIIKIIKAIIDIFAK
Physicochemical Analysis
1856.34 Da
9.70
1.73
1.52
0.1019
1.52
0.71
0.48
-15.56
189.41
0.0588
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
664.51
-0.71
23.0
23.0
65.0
131.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0060394 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus group A serotype M3 4041-05
10 μM
MIC
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
RECORD: Rec_0087239 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus USA 300
64 μM
MIC
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
RECORD: Rec_0140493 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human erythrocytes
10 μg/mL
Hemolysis
PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
RECORD: Rec_0144811 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Toxic Hemolytic Immunosuppressive
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0173723 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Immunosuppressive Antimicrobial
Human erythrocytes
10 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/22371493/ PMID22371493 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22371493/
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