Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 2.9

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length39 amino acids

Chemical FormulaC181H299N53O52S7

DescriptionStandard

        TIINVKCTSPKQCLKPCKDLYGPHAGAKCMNGKCKCYNN
    

Molecular Weight4274.09 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.42

Net Charge (pH 7.4) 5.08

Charge Density (pH 7.0) 0.1389

GRAVY Index-0.54

Hydrophobic Moment 0.57

Boman Index-0.11

Instability Index29.63

Aliphatic Index 52.56

Aromaticity 0.0513

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1707.47

LogP -19.79

H-bond Donors 62.0

H-bond Acceptors 66.0

Rotatable Bonds 142.0

Heavy Atoms 293.0

Ring Count 6.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0192047 VERIFIED: NO

Provenance & Taxonomy

OrganismCentruroides elegans [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Disulfide7-29; 13-34; 17-36

Bio-Activity Profile

Function

Toxin

TargetKv1