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MYP_061976
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
3 amino acids
C18H37N5O4
Standard
Sequence
LKK
Physicochemical Analysis
387.52 Da
10.00
1.76
1.55
0.5860
-1.33
0.97
-0.65
-21.63
130.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
173.56
-0.33
6.0
6.0
15.0
27.0
0.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006140 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic Antileukemic
Lymphocytes
PaperIsolation and characterization of cytotoxic small peptides, α-casecidins, from bovine αs1-casein digested with bovine trypsin | Otani, H. et al. | DOI: 10.1046/j.1344-3941.2003.00135.x Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0041247 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli ATCC 25922
3.1 μM
MIC
PMID26257894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26257894/
RECORD: Rec_0059361 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
<12.5 μM
Hemolysis
PMID26257894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26257894/
RECORD: Rec_0065255 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 10231
25 μM
MIC
PMID26257894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26257894/
RECORD: Rec_0074032 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Toxic
PaperOtani H., Suzuki H.. Isolation and characterization of cytotoxic small peptides, alpha-casecidins, from bovine alpha s1-casein digested with bovine trypsin. Anim. Sci. J., 74, 427-435, 2003.
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