Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC862H1369N253O249S11

DescriptionStandard

        MNAKIRYGLSAAVLALIAVGAPAPDILDQFLDEKEGNHTTAYRDGSGIWTICRGATMVGGKPVFPGMKLSKEKCDQVNAIERDKALAWVDRNIKVTLTEPQKAGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDRGRDCRLRSNNCYGQVIRRDQESALACWGIEQ
    

Molecular Weight19613.35 Da

Isoelectric Point (pI)9.16

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.09

Charge Density (pH 7.0) 0.0425

GRAVY Index-0.37

Hydrophobic Moment 0.64

Boman Index-0.05

Instability Index40.23

Aliphatic Index 76.72

Aromaticity 0.0847

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8123.42

LogP -86.24

H-bond Donors 291.0

H-bond Acceptors 269.0

Rotatable Bonds 652.0

Heavy Atoms 1375.0

Ring Count 29.0

Amide Bonds 190.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0372723 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence