Peptide Database

Peptide NameCurvacin A / sakacin A

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC188H283N53O56S2

DescriptionStandard

        RSYGNGVYCNNSKCWVNWGEAKENIAGIVISGWASGLAGI
    

Molecular Weight4245.71 Da

Isoelectric Point (pI)8.02

Net Charge (pH 7.0)0.74

Net Charge (pH 7.4) 0.50

Charge Density (pH 7.0) 0.0185

GRAVY Index-0.04

Hydrophobic Moment 0.36

Boman Index0.19

Instability Index11.52

Aliphatic Index 80.50

Aromaticity 0.1250

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1770.96

LogP -19.47

H-bond Donors 64.0

H-bond Acceptors 59.0

Rotatable Bonds 136.0

Heavy Atoms 299.0

Ring Count 8.0

Amide Bonds 44.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009595 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterococcus mundtii [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)