Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC144H212N38O39S2

DescriptionStandard

        VAPAQHLCGSHLVDALYLVCGDRGFFYNP
    

Molecular Weight3163.58 Da

Isoelectric Point (pI)5.97

Net Charge (pH 7.0)-1.11

Net Charge (pH 7.4) -1.46

Charge Density (pH 7.0) -0.0383

GRAVY Index0.38

Hydrophobic Moment 0.34

Boman Index0.26

Instability Index22.48

Aliphatic Index 94.14

Aromaticity 0.1379

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1201.27

LogP -9.39

H-bond Donors 42.0

H-bond Acceptors 42.0

Rotatable Bonds 94.0

Heavy Atoms 223.0

Ring Count 8.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174459 VERIFIED: NO

Provenance & Taxonomy

OrganismLophius americanus [Animal]

FamilyInsulin

Tax ID8073

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0321165 VERIFIED: NO

Provenance & Taxonomy

OrganismLophius americanus [Animal]

FamilyInsulin

Tax ID8073

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0382454 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/