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MYP_061928
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Basic Information
cecropin B analog (CB-1)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C194H323N55O41S
Standard
Sequence
KWKVFKKIEKMGRNIRNGIVKAGPKWKVFKKIEK
Physicochemical Analysis
4114.05 Da
10.93
10.75
10.53
0.3163
-0.90
0.89
-0.27
36.23
74.41
0.1176
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1617.21
-7.92
57.0
53.0
150.0
291.0
7.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0165128 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa LC
1.48
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
RECORD: Rec_0226234 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
RECORD: Rec_0246787 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0265625 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lymphoblastic leukemia CCRF-CEM
8.6
IC50
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
RECORD: Rec_0291518 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Mouse fibroblasts 3T6 50% Cell death at >50 microM
3 μM
Hemolysis
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
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