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MYP_061928
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Basic Information
cecropin B analog (CB-1)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
34 amino acids
C194H323N55O41S
Standard
Sequence
KWKVFKKIEKMGRNIRNGIVKAGPKWKVFKKIEK
Physicochemical Analysis
4114.05 Da
10.93
10.75
10.53
0.3163
-0.90
0.89
-0.27
36.23
74.41
0.1176
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1617.21
-7.92
57.0
53.0
150.0
291.0
7.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042081 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperWang W., Smith D. K., Moulding K., Chen H. M.. The dependence of membrane permeability by the antibacterial peptide cecropin B and its analogs, CB-1 and CB-3, on liposomes of different composition. J. Biol. Chem., 273, 27438-27448, 1998.
RECORD: Rec_0073645 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
RECORD: Rec_0111075 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae LC
0.39
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
RECORD: Rec_0154076 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human promyelocytic leukemia HL-60
7.5
IC50
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
RECORD: Rec_0165095 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Jurkat cells E6-1
2.4
IC50
PMID11004545 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11004545/
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