Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length153 amino acids

Chemical FormulaC759H1192N220O221S8

DescriptionStandard

        MMVSKVQFNPRSRTDAIFVHCSATKPEMDIGVETIRMWHKQQGWLDVGYHFIIKRDGTVEEGRPVNVVGSHVKDWNSRSVGVCLVGGIDAKGQFEANFTPAQMNSLRNKLADLKVLYPQAEIKAHHDVAPKACPSFDLQRWLSTNELVTSDRG
    

Molecular Weight17191.45 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.01

Net Charge (pH 7.4) 1.41

Charge Density (pH 7.0) 0.0132

GRAVY Index-0.37

Hydrophobic Moment 0.57

Boman Index-0.03

Instability Index43.97

Aliphatic Index 77.65

Aromaticity 0.0784

Extinction Coeff. Reduced 24980.00

Extinction Coeff. Oxidized 25105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7099.26

LogP -71.36

H-bond Donors 247.0

H-bond Acceptors 237.0

Rotatable Bonds 569.0

Heavy Atoms 1208.0

Ring Count 29.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0188104 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoP_F [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic