Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC447H714N134O142S9

DescriptionStandard

        MNSLGTACFAVLCLFAIVSTGNGFPQESADRVQSFANTLFDELPEQSYQAAAENLRLKRATCDLLSGLGVNDSACAAHCIARGNRGGYCNSKKVCVCRN
    

Molecular Weight10525.85 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.52

Net Charge (pH 7.4) 0.12

Charge Density (pH 7.0) 0.0052

GRAVY Index0.01

Hydrophobic Moment 0.61

Boman Index0.04

Instability Index41.71

Aliphatic Index 77.98

Aromaticity 0.0707

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4474.38

LogP -57.16

H-bond Donors 162.0

H-bond Acceptors 153.0

Rotatable Bonds 348.0

Heavy Atoms 732.0

Ring Count 10.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0272987 VERIFIED: NO

Provenance & Taxonomy

OrganismCulex quinquefasciatus [Animal]

FamilyDefensin

Tax ID7176

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal