Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length644 amino acids

Chemical FormulaC3025H4744N814O918S14

DescriptionStandard

        MSDYDFNGGVPPLPGNVWLPADEYGPGRWVAPTTGSQAGNILTVWPSNGYTPPDTSYLPPSTLGPGWADYDMAGVASDQGYLVYGVPVRVVLDILTEEGDWPGWTIGLYEAYREQEPVSAAIATLDRGLISGLPDPSRPAVVPYARLEPESPHPEKISCVMTIQPLNNVTDVPVNALPASGRTVNVQRRLTDLVFGGNQYLVVTGGKPMSVRVVDAGLVKDKTPQSDRFLKNTYQATIAPGLPPLIFTTDYINDSRMFPKNYAPNASGIISGQGVYGPAGYTSSDRNDDVIVRFPAGSGASPLYISSVEVLNPESLHQRQLAETDIRNRIDAAIKAEENRKYLFGKAGIQETPAFTPEMVKSASALLAAPAAMMLNRAPAGIQLSATGTGVMTAVGEWAGSIAGALWRGAVGTAAASTAGPMVAAASTLFFSRPAGEGSDKVPGRDINMMAAQVSLFNTGKVKIDPGMKTVDLPVRGFISTDSNGRQSVKLVRTGAGGVPATVPVLSAVRDKVTGLDKITVPAVAGAPSRTILVNPVPVGPAAPSHTGNSTPVPVTPVHTGTDVKQADSIVTTTLPAADIPALQDFIYWQPDATGTGVEPIYVVFSSPPKSFSHGYKHYPPKGVPWKDIVKSTANGGEAKSLSQ
    

Molecular Weight67651.84 Da

Isoelectric Point (pI)5.81

Net Charge (pH 7.0)-4.94

Net Charge (pH 7.4) -5.60

Charge Density (pH 7.0) -0.0077

GRAVY Index-0.11

Hydrophobic Moment 0.69

Boman Index0.12

Instability Index37.85

Aliphatic Index 82.38

Aromaticity 0.0730

Extinction Coeff. Reduced 87780.00

Extinction Coeff. Oxidized 87780.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166825 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella michiganensis [Bacterium]

FamilyPyocin/Colicin

Tax ID1134687

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli