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MYP_061873
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Basic Information
Kassinatuerin-1 (Frogs, amphibians, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C109H175N25O26S
Standard
Sequence
GFMKYIGPLIPHAVKAISDLI
Physicochemical Analysis
2283.77 Da
8.51
0.85
0.59
0.0403
0.83
0.61
0.42
6.78
134.76
0.0952
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
786.22
-2.02
26.0
29.0
72.0
161.0
5.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0283455 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Horse erythrocytes
120 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/19427345/ PMID19427345 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19427345/
RECORD: Rec_0292409 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
PMID15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15885852/
RECORD: Rec_0301611 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
PMID15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15885852/
RECORD: Rec_0305190 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli
6.25 μM
MIC
PMID10679222;15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10679222/
RECORD: Rec_0308614 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
65 μM
LD50
Paperhttps://pubmed.ncbi.nlm.nih.gov/15885852/ PMID15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15885852/
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