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MYP_061873
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Basic Information
Kassinatuerin-1 (Frogs, amphibians, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C109H175N25O26S
Standard
Sequence
GFMKYIGPLIPHAVKAISDLI
Physicochemical Analysis
2283.77 Da
8.51
0.85
0.59
0.0403
0.83
0.61
0.42
6.78
134.76
0.0952
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
786.22
-2.02
26.0
29.0
72.0
161.0
5.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0119761 VERIFIED: NO
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Hemolytic
RECORD: Rec_0137272 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Hemolytic
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0139531 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Klebsiella pneumoniae
25 μM
MIC
PMID10679222;15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10679222/
RECORD: Rec_0152303 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Kassinatuerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
PaperJ.M. Conlon et al. / Peptides 26 (2005) 2104-2110. Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives Evidence URLhttps://www.uniprot.org/uniprotkb/P0C010/entry
RECORD: Rec_0165474 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Kassinatuerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
6.25 μM
MIC
PaperJ.M. Conlon et al. / Peptides 26 (2005) 2104-2110. Antimicrobial and cytolytic properties of the frog skin peptide, kassinatuerin-1 and its L- and D-lysine-substituted derivatives Evidence URLhttps://www.uniprot.org/uniprotkb/P0C010/entry
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