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MYP_061873
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Basic Information
Kassinatuerin-1 (Frogs, amphibians, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
21 amino acids
C109H175N25O26S
Standard
Sequence
GFMKYIGPLIPHAVKAISDLI
Physicochemical Analysis
2283.77 Da
8.51
0.85
0.59
0.0403
0.83
0.61
0.42
6.78
134.76
0.0952
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
786.22
-2.02
26.0
29.0
72.0
161.0
5.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006250 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Cytotoxic
Display cytotoxicity against L929 fibroblasts
12 μM
LD50
PMID10679222;15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10679222/
RECORD: Rec_0020579 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
PMID15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15885852/
RECORD: Rec_0026273 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecalis
12.5 μM
MIC
PMID10679222;15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10679222/
RECORD: Rec_0032057 VERIFIED: NO
Provenance & Taxonomy
African frog [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0034809 VERIFIED: YES
Provenance & Taxonomy
Kassina senegalensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Cytolytic Hemolytic
No Target Organism Found
PMID10679222;15885852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10679222/
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