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MYP_061823
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
7 amino acids
C39H62N10O12
Standard
Sequence
VPSERYL
Physicochemical Analysis
862.97 Da
5.97
-0.26
-0.48
-0.0377
-0.53
0.34
-0.13
80.34
97.14
0.1429
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
368.79
-2.42
13.0
12.0
25.0
61.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011521 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
alpha-S1-Casein-derived
9940
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
249.5 μM
IC50
PaperAngiotensin converting enzyme-inhibitory activity of peptides isolated from Manchego cheese Stability under simulated gastrointestinal digestion | Gomez-Ruiz, JA. et al. | DOI: 10.1016/j.idairyj.2004.04.007 Evidence URLhttps://www.uniprot.org/uniprotkb/P04653/entry
RECORD: Rec_0023698 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0075866 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
ACE-inhibitory peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
249.5 μM
IC50
PaperWhey Proteins as Source of Bioactive Peptides Against Hypertension
RECORD: Rec_0121530 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal] [Animal]; Bos taurus [Animal]
Casein-derived peptide
9940;9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
94.2 ± 0.5 μM
IC50
RECORD: Rec_0196281 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
9940
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperAngiotensin-converting enzyme-inhibitory peptides in Manchego cheeses manufactured with different starter cultures
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