Peptide Database

Peptide NameDefensin alpha 10

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC423H681N121O135S8

DescriptionStandard

        MRTLTLLTALLLLLHTQAESPQGSPKEAPDQEQLDMEDQDISVFFGGDKGTALQDAAGSTCSCRIGTCVSGEWLSWVCRINGRIYRLCCR
    

Molecular Weight9878.18 Da

Isoelectric Point (pI)4.90

Net Charge (pH 7.0)-3.45

Net Charge (pH 7.4) -3.82

Charge Density (pH 7.0) -0.0384

GRAVY Index-0.12

Hydrophobic Moment 0.77

Boman Index0.02

Instability Index31.80

Aliphatic Index 85.67

Aromaticity 0.0556

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4125.93

LogP -46.04

H-bond Donors 150.0

H-bond Acceptors 141.0

Rotatable Bonds 328.0

Heavy Atoms 687.0

Ring Count 11.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346287 VERIFIED: NO

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyDefensin

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence