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MYP_061773
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Basic Information
Brevinin-1RTa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
24 amino acids
C124H207N31O27S2
Standard
Sequence
FLPLLAGVVANFLPQIICKIARKC
Physicochemical Analysis
2628.29 Da
9.50
2.74
2.50
0.1141
1.26
0.77
0.37
23.86
150.42
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
915.16
-3.11
32.0
32.0
84.0
184.0
4.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0206622 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Staphylococcus aureus
6.3 μg/mL
MIC
RECORD: Rec_0207956 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
RECORD: Rec_0216814 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa 1
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
RECORD: Rec_0216939 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
rabbit red blood cells
100 μg/mL
LD50
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
RECORD: Rec_0253440 VERIFIED: YES
Provenance & Taxonomy
Amolops ricketti [Animal]
Brevinin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit erythrocytes
100 μg/mL
LD50
PMID22100518 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22100518/
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