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MYP_061760
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Basic Information
Temporin-HN2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
14 amino acids
C73H133N19O19
Standard
Sequence
NILNTIINLAKKIL
Physicochemical Analysis
1580.95 Da
10.00
1.76
1.55
0.1256
0.87
0.68
0.28
56.06
202.14
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
643.16
-3.69
21.0
21.0
56.0
111.0
0.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0186364 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
S. carnosus KHS
19 μM
MIC
PaperNovel antimicrobial peptides isolated from the skin secretions of Hainan odorous frog, Odorrana hainanensis.
RECORD: Rec_0208871 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 71.4%, E 0.0%, T 0.0%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0213632 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
4.8 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0218954 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans ATCC2002
9.5 μM
MIC
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
RECORD: Rec_0229713 VERIFIED: YES
Provenance & Taxonomy
Odorrana hainanensis [Animal]
Temporin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Hemolytic activity against human erythrocytes
300 μM
LC50
PMID22450466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22450466/
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