Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC548H877N145O169S3

DescriptionStandard

        PDLSGYEKFGLGNVKYNISKIHVTAVEFPSASISLLPGTGIKLVIGNASLTIDMNWNIRTWMFKDNGRSTVYISKVSVTAIFSTPLDNTGHTSISLTSCRTTSGDIDIKLNGKS
    

Molecular Weight12296.89 Da

Isoelectric Point (pI)9.20

Net Charge (pH 7.0)3.12

Net Charge (pH 7.4) 2.93

Charge Density (pH 7.0) 0.0274

GRAVY Index-0.01

Hydrophobic Moment 0.44

Boman Index0.12

Instability Index11.90

Aliphatic Index 93.16

Aromaticity 0.0789

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5044.08

LogP -57.43

H-bond Donors 180.0

H-bond Acceptors 177.0

Rotatable Bonds 407.0

Heavy Atoms 865.0

Ring Count 17.0

Amide Bonds 121.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0053339 VERIFIED: NO

Provenance & Taxonomy

OrganismArdeotis kori [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria