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MYP_061742
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Basic Information
BacP2R-NH2 (cyclic derivative of bactenecin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
12 amino acids
C63H119N27O13S2
Standard
Sequence
RLCPRVRIRVCR
Physicochemical Analysis
1526.92 Da
11.82
4.74
4.51
0.3950
-0.20
0.44
-0.61
18.93
113.33
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
684.13
-6.18
29.0
20.0
50.0
105.0
1.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033077 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterococcus faecalis ATCC 29212
32 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0056112 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis C621
16 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0062017 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa K799
16 μg/mL
MIC
PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
RECORD: Rec_0086928 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6172185 B1 Evidence URLhttps://patents.google.com/patent/US6172185B1/en PatentUS 6172185 B1
RECORD: Rec_0104531 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
3-11
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa K799
16 μg/mL
MIC
PaperImproved derivatives of bactenecin, a cyclic dodecameric antimicrobial cationic peptide. Antimicrob Agents Chemother. 1999 May;43(5):1274-1276. doi: 10.1128/AAC.43.5.1274. PMID: 10223951. PMID10223951 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10223951/
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