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MYP_061722
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Basic Information
Scolopendrasin II
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
21 amino acids
C113H199N31O28S
Standard
Sequence
KYALMKKIAELIPNLKSRQVK
Physicochemical Analysis
2472.04 Da
10.30
4.76
4.54
0.2265
-0.39
0.67
-0.16
24.72
116.19
0.0476
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
992.47
-5.87
34.0
34.0
89.0
173.0
2.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0132993 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0143548 VERIFIED: NO
Provenance & Taxonomy
Scolopendra subspinipes [Animal]; Animalia [Animal]
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Penicillamine
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0202912 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Scolopendrasin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperJ Microbiol Biotechnol. 2013 Oct 28;23(10):1381-5. | http://www.ncbi.nlm.nih.gov/pubmed/23801249 PMID23801249 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23801249/
RECORD: Rec_0234912 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0356239 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Scolopendra subspinipes mutilans [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli, P. acnes, S. pyogenes, Staphylococcus epidermidis
PaperAntimicrobial activity of the synthetic peptide scolopendrasin II from the centipede Scolopendra subspinipes mutilans
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