Peptide Database

Peptide NameAdalimumab

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TNF-alpha inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length236 amino acids

Chemical FormulaC1127H1767N311O365S6

DescriptionStandard

        DIQMTQSPSSLSASVGDRVTITCRASQGIRNYLAWYQQKPGKAPKLLIYAASTLQSGVPSRFSGSGSGTDFTLTISSLQPEDVATYYCQRYNRAPYTFGQGTKVEIKRTVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQSGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGECHEAVYEVQLVESGGGLVQPGRS
    

Molecular Weight25705.34 Da

Isoelectric Point (pI)8.24

Net Charge (pH 7.0)1.99

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.0084

GRAVY Index-0.45

Hydrophobic Moment 0.59

Boman Index-0.03

Instability Index54.17

Aliphatic Index 69.79

Aromaticity 0.0890

Extinction Coeff. Reduced 28880.00

Extinction Coeff. Oxidized 29130.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057388 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Cricetulus griseus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10029

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TNF inhibitor

Half-Life240-480 h