Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length138 amino acids

Chemical FormulaC718H1113N205O210S4

DescriptionStandard

        GRWYPWLLLLGLVVSSTSAQDLSYREAVLRAVDQLNERSSEANLYRLLELEPPPKDDEDLGTRKPVSFTVKETVCPRTTQQPAEQCDFKEEGRVKQCVGTVTLDPSNDQFDLNCNALQSVRIRFPWPWRWPWWRRVRG
    

Molecular Weight16105.03 Da

Isoelectric Point (pI)6.53

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.55

Charge Density (pH 7.0) -0.0018

GRAVY Index-0.65

Hydrophobic Moment 0.69

Boman Index-0.14

Instability Index49.45

Aliphatic Index 77.61

Aromaticity 0.1014

Extinction Coeff. Reduced 42970.00

Extinction Coeff. Oxidized 43220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6734.03

LogP -63.72

H-bond Donors 238.0

H-bond Acceptors 214.0

Rotatable Bonds 517.0

Heavy Atoms 1137.0

Ring Count 32.0

Amide Bonds 150.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0228029 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence