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MYP_061652
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Basic Information
CPG2000
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
RGGRLCYCRRRFCVCVGRX
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0005592 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da] at 19; mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. typhimurium 14028
4 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0010562 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da] at 19; mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
S. typhimurium 14028
8 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0014110 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da] at 19; mPEG2000 [polyethylene glycol monomethyl ether(mPEG) 2000 Da]
Bio-Activity Profile
Hemolytic
human RBCs
128 μg/mL
HC10
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0041096 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da] at 19; mPEG750 [polyethylene glycol monomethyl ether(mPEG) 750 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 29213
16 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
RECORD: Rec_0042590 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
mPEG1000 [polyethylene glycol monomethyl ether(mPEG) 1000 Da] at 19; mPEG1000 [polyethylene glycol monomethyl ether(mPEG) 1000 Da]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 25922
16 μg/mL
MIC
PMID34196552 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34196552/
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