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MYP_061639
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Basic Information
Unnamed
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
35 amino acids
C174H285N47O46
Standard
Sequence
GFGSLFKFLAKKVAKTVAKQAAKQGAKYIANKQTE
Physicochemical Analysis
3771.41 Da
10.30
6.76
6.54
0.1931
-0.34
0.69
-0.03
33.10
70.00
0.1143
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1551.46
-14.64
53.0
53.0
134.0
267.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0281445 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cationic peptide 04 (cupiennin); 01 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Non-hemolytic
Pseudomonas aeruginosa
PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0310023 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperCupiennin 1, a New Family of Highly Basic Antimicrobial Peptides in the Venom of the Spider Cupiennius salei (Ctenidae)
RECORD: Rec_0327996 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 57.1%, E 0.0%, T 28.6%, C 14.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Cytotoxic
PaperIn silico approach for predicting toxicity of peptides and proteins PMID24058508 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24058508/
RECORD: Rec_0344342 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Cationic peptide 04 (cupiennin); 01 subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Toxin Non-hemolytic
Escherichia coli
PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
RECORD: Rec_0353261 VERIFIED: YES
Provenance & Taxonomy
Cupiennius salei [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
PaperPubMed PMID: 11792701 PMID11792701 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11792701/
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