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MYP_061544
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Basic Information
Temporin-TP1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
16 amino acids
C83H144N18O17
Standard
Sequence
FLPVLGKVIKLVGGLL
Physicochemical Analysis
1666.14 Da
10.00
1.76
1.55
0.1099
1.77
0.55
0.60
14.63
200.62
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.07
0.82
18.0
19.0
55.0
118.0
2.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009408 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
110118
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
E.cloacae CGMCC 1.57
>100 μM
MIC
PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0021187 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Temporin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24675879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24675879/
RECORD: Rec_0040324 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0042302 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecium 091299
PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
RECORD: Rec_0047711 VERIFIED: YES
Provenance & Taxonomy
Hylarana taipehensis [Animal]
Temporin
110118
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antioxidant
fungi C. glabrata 090902
50 μM
MIC
PaperIdentification of multiple peptides with antioxidant and antimicrobial activities from skin and its secretions of Hylarana taipehensis, Amolops lifanensis, and Amolops granulosus PMID25066917 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25066917/
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