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MYP_061525
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Basic Information
M3
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C77H126N28O17S2
Standard
Sequence
KCFQWQRNMRKVR
Physicochemical Analysis
1780.13 Da
11.72
4.75
4.53
0.3652
-1.64
0.60
-0.70
6.39
22.31
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
795.32
-7.02
30.0
24.0
62.0
124.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0173256 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Lactoferrin-derived
9606
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli; Staphylococcus aureus; Candida albicans; Klebsiella pneumoniae; Pseudomonas aeruginosa; Enterococcus faecalis
MMC99
PaperStructure-microbicidal activity relationship of synthetic fragments derived from the antibacterial α-helix of human lactoferrin | Haversen, L. et al. | DOI: 10.1128/AAC.00908-09 Evidence URLhttps://www.uniprot.org/uniprotkb/P02788/entry
RECORD: Rec_0208585 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
200 μg/mL
MFC
PMID19917761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19917761/
RECORD: Rec_0239155 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Lactoferrin-derived
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: Labelled with fluoresceine
Bio-Activity Profile
Cell-penetrating peptide Antimicrobial
HeLa
Fluorescence-based uptake assay
PMID19858187 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19858187/
RECORD: Rec_0256946 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
RECORD: Rec_0279542 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
50 μg/mL
MFC
PMID19917761 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19917761/
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