‹ ›
MYP_061509
← PREVIOUS NEXT → BACK
Basic Information
Gaegurin-5 (1-13)[K7H,V8A,A9L,V12L], PTP-7a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C71H112N16O15
Standard
Sequence
FLGALFHALSKLL
Physicochemical Analysis
1429.75 Da
8.76
0.85
0.59
0.0651
1.53
0.46
0.56
-3.83
165.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
487.45
-0.31
17.0
17.0
46.0
102.0
3.0
12.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0121026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID22934601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22934601/
RECORD: Rec_0125242 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
28 μM
IC50
PaperPubMed PMID: 22934601 PMID22934601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22934601/
RECORD: Rec_0135400 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli O157
64 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0192674 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human lung carcinoma A549
52
IC50
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0193943 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 25923
2 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
FIRST PREV 1 2 3 4 5 6 NEXT LAST
Showing 5 records on this page · Page 3 of 6