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MYP_061509
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Basic Information
Gaegurin-5 (1-13)[K7H,V8A,A9L,V12L], PTP-7a
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C71H112N16O15
Standard
Sequence
FLGALFHALSKLL
Physicochemical Analysis
1429.75 Da
8.76
0.85
0.59
0.0651
1.53
0.46
0.56
-3.83
165.38
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
487.45
-0.31
17.0
17.0
46.0
102.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0021098 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus epidermidis ATCC 9709
4 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0053367 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
0.5 % hemolysis at 7.5 μM
Hemolysis
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0055944 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Gaegurin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Micrococcus luteus ATCC 10420
2 μM
MIC
PMID19464332;22526264 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19464332/
RECORD: Rec_0069534 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
A-549
28 μM
IC50
PMID22934601 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22934601/
RECORD: Rec_0082393 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
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