Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length45 amino acids

Chemical FormulaC220H344N68O62S5

DescriptionStandard

        NFEHSCNGYMRPHPRGLCGEDLHVIISNLCSSLGGNRRFLAKYMV
    

Molecular Weight5093.83 Da

Isoelectric Point (pI)8.66

Net Charge (pH 7.0)2.00

Net Charge (pH 7.4) 1.59

Charge Density (pH 7.0) 0.0443

GRAVY Index-0.26

Hydrophobic Moment 0.54

Boman Index-0.01

Instability Index45.18

Aliphatic Index 75.78

Aromaticity 0.0889

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2091.44

LogP -22.01

H-bond Donors 76.0

H-bond Acceptors 72.0

Rotatable Bonds 166.0

Heavy Atoms 355.0

Ring Count 9.0

Amide Bonds 48.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004545 VERIFIED: NO

Provenance & Taxonomy

OrganismAplysia californica [Animal]

FamilyInsulin

Tax ID6500

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0277835 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/