MYP_061429
Basic Information
Lacticin 3147 A1 (LtnA1; Bacteriocin; Preclinical)
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Antimicrobial Antibacterial
Antimicrobial Antibacterial Anti-Gram-positive
Reproductive biology Contraceptive activity Spermicidal
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin Toxic
Standard
30 amino acids
C148H209N39O46S5
Standard
Sequence
CSTNTFSLSDYWGNNGAWCTLTHECMAWCK
Physicochemical Analysis
3430.80 Da
5.32
-1.19
-1.51
-0.0397
-0.29
0.27
0.11
28.85
32.67
0.1667
17990.00
18240.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1375.00
-15.75
53.0
51.0
104.0
238.0
9.0
32.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0391325 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis [Bacterium]
Bacteriocin
1358
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
produced by the food-grade organism Lactococcus lactis
Bio-Activity Profile
Antimicrobial Spermicidal
Enterococcus faecium
1.9-3.8 μg/mL
MIC
RECORD: Rec_0406731 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0419801 VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis subsp. lactis [Bacterium]
Bacteriocin
Structure & Mods
thioether-constrained cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
None
None
There are two 2,3-dehydrobutyrines (T3; T5), one 2,3-didehydroalanine (S7), two Lanthionines (C1-S2; S9-C19) and two Beta-methyllanthionines (T20-C25; T22-C29)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Lactobacillus
Showing 3 records on this page · Page 3 of 3