Peptide Database

Peptide NameEsculentin-2-OG15 antimicrobial peptide

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC376H627N97O112S6

DescriptionStandard

        MFTMKKPLLVLFFLGTISLSLCQEERAADEEDNGEVEEVKRGLFTLIKGAAKLIGKAVAKEAGKTGLELMACKITNQC
    

Molecular Weight8490.97 Da

Isoelectric Point (pI)6.25

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0065

GRAVY Index0.12

Hydrophobic Moment 0.64

Boman Index0.08

Instability Index17.71

Aliphatic Index 100.13

Aromaticity 0.0513

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3377.48

LogP -28.26

H-bond Donors 118.0

H-bond Acceptors 118.0

Rotatable Bonds 300.0

Heavy Atoms 591.0

Ring Count 5.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0311043 VERIFIED: NO

Provenance & Taxonomy

OrganismOdorrana grahami [Animal]

Tax ID167935

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0416671 VERIFIED: NO