Peptide Database

Peptide NameAntimicrobial peptide brevinin-2ZHa

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length77 amino acids

Chemical FormulaC370H626N100O107S6

DescriptionStandard

        MLTLKKSMLLLFFLGTISLSLCQEERGAGEDEVIEEEVKRGIMRVFKGVLKTAGKSVAKNVAGSFLDRLKCKISGGC
    

Molecular Weight8379.92 Da

Isoelectric Point (pI)9.18

Net Charge (pH 7.0)3.48

Net Charge (pH 7.4) 3.20

Charge Density (pH 7.0) 0.0452

GRAVY Index0.19

Hydrophobic Moment 0.87

Boman Index0.06

Instability Index20.75

Aliphatic Index 103.77

Aromaticity 0.0519

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3360.65

LogP -29.89

H-bond Donors 122.0

H-bond Acceptors 117.0

Rotatable Bonds 300.0

Heavy Atoms 583.0

Ring Count 4.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0051799 VERIFIED: YES

Provenance & Taxonomy

OrganismRana zhenhaiensis [Animal]

FamilyBrevinin

Tax ID120508

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal