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MYP_061396
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Basic Information
cHLH-pDI1-R
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
40 amino acids
C195H318N64O56S
Standard
Sequence
GARELRRLERELRRLEKGGGGGGKLAALTFEHYWAQLTSC
Physicochemical Analysis
4487.07 Da
9.77
2.85
2.57
0.0712
-0.68
1.12
-0.19
68.94
78.25
0.0750
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1976.64
-19.88
74.0
61.0
155.0
316.0
5.0
40.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008537 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
>64 μM
Hemolysis
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0046841 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MCF-10A
64 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0049301 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
MM96L
64 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0063205 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: K562
64 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
RECORD: Rec_0064855 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
CAA, Chloroacetic acid
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HFF-1
64 μM
CC50
PMID31390185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31390185/
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