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MYP_061369
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Basic Information
Nigrocin-2HSa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
21 amino acids
C87H149N23O24S2
Standard
Sequence
GLLGSLFGAGKKVACALSGLC
Physicochemical Analysis
1965.38 Da
8.90
1.74
1.50
0.0828
1.19
0.43
0.43
18.32
120.95
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
737.82
-7.46
28.0
28.0
66.0
136.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0048662 VERIFIED: YES
Provenance & Taxonomy
Rana hosii,Odorrana hosii [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
28 μM
MIC
RECORD: Rec_0073427 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0074713 VERIFIED: YES
Provenance & Taxonomy
Odorrana hosii [Animal]
Nigrocin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
28.0 μM
MIC
PaperJ.M. Conlon et al. / Toxicon 52 (2008) 465-473. Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae) PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
RECORD: Rec_0155480 VERIFIED: YES
Provenance & Taxonomy
Odorrana hosii [Animal]
Nigrocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
15-21
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus
56 μM
MIC
PaperCharacterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae). PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
RECORD: Rec_0186904 VERIFIED: YES
Provenance & Taxonomy
Odorrana hosii [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PaperCharacterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae) PMID18621071 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18621071/
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