‹ ›
MYP_061341
← PREVIOUS NEXT → BACK
Basic Information
IN(11-20)
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition
Standard
11 amino acids
C68H109N15O14
Standard
Sequence
WFVLLTITVLR
Physicochemical Analysis
1360.68 Da
9.75
0.76
0.56
0.0691
1.85
0.28
0.55
26.60
194.55
0.1818
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
472.47
0.73
18.0
15.0
41.0
97.0
3.0
10.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0336482 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
inhibition of intergration
23 %
Inhibition
PaperPubMed PMID: 19850483 PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0340094 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HIV-1 Replication inhibition
HIV-1
62.5 μM
% inhibition
Mammalian: 2.8 h; Yeast: 3 min; E. coli: 2 min
PaperPeptide inhibitors of HIV-1 integrase: from mechanistic studies to improved lead compounds. | Maes M, Levin A, Hayouka Z, Shalev DE, Loyter A, Friedler A. | Bioorg Med Chem. 2009 Nov 15;17(22):7635-42. | DOI:10.1016/j.bmc.2009.09.053 | PMID:19850483 PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0392428 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1[20-30% IN activity = 19.5 microM]
PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
RECORD: Rec_0392551 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Replication inhibition
inhibition of virus replication in TZM-bl cells
62.5 μM
% inhibition
Mammalian: 2.8 h; Yeast: 3 min; E. coli: 2 min
PaperPeptide inhibitors of HIV-1 integrase: from mechanistic studies to improved lead compounds. | Maes M, Levin A, Hayouka Z, Shalev DE, Loyter A, Friedler A. | Bioorg Med Chem. 2009 Nov 15;17(22):7635-42. | DOI:10.1016/j.bmc.2009.09.053 | PMID:19850483 PMID19850483 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19850483/
FIRST PREV 1 2
Showing 4 records on this page · Page 2 of 2