Peptide Database

Peptide NameLL-I/3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC87H155N23O17

DescriptionStandard

        VNWKKVLKKIIKVAK
    

Molecular Weight1795.31 Da

Isoelectric Point (pI)10.70

Net Charge (pH 7.0)5.73

Net Charge (pH 7.4) 5.51

Charge Density (pH 7.0) 0.3819

GRAVY Index-0.04

Hydrophobic Moment 0.84

Boman Index-0.09

Instability Index-25.88

Aliphatic Index 142.67

Aromaticity 0.0667

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 685.72

LogP -1.31

H-bond Donors 24.0

H-bond Acceptors 23.0

Rotatable Bonds 66.0

Heavy Atoms 127.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240670 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis

Activity0.7 μM

MethodMIC

PaperLasioglossins: three novel antimicrobial peptides from the venom of the eusocial bee Lasioglossum laticeps (Hymenoptera: Halictidae). Chembiochem. 2009 Aug 17;10(12):2089-99. doi: 10.1002/cbic.200900133. PMID: 19591185. PMID19591185 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19591185/

RECORD: Rec_0364725 VERIFIED: YES