Peptide Database

Peptide Namebeta-Defensin 126

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC210H334N62O60S8

DescriptionStandard

        NWYVKKCLNDVGICKKNCKPEEMHVKNGWAMCGKQRDCCVPAD
    

Molecular Weight4943.80 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0649

GRAVY Index-0.70

Hydrophobic Moment 0.46

Boman Index-0.16

Instability Index33.70

Aliphatic Index 49.77

Aromaticity 0.0698

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1994.42

LogP -19.04

H-bond Donors 72.0

H-bond Acceptors 72.0

Rotatable Bonds 166.0

Heavy Atoms 340.0

Ring Count 8.0

Amide Bonds 47.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0405213 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide7-38; 14-32; 18-39

Bio-Activity Profile

Function

Antimicrobial Antibacterial