Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length456 amino acids

Chemical FormulaC2304H3633N619O651S11

DescriptionStandard

        TNPGFVVRITQAGLDYAHQHGIAILEKELARLKLPDISGDSRVLRVGKVHYELSRLRLRDFHLPYSRITPISNMGLQVSISNAFAELDGDWRVKFYFVRDHGSFDVKVENVYIKIILKLGSDNGGKPLISTSDCSTRISKVHVLFSGKFGWLYNLFHSAIESRFRKILEEKVCDIVAKSVHDDLQTYIRTLPVTARIDDKTGIDYSLVASPRATAQSLDADLKGEFYSLAHRSTVPFSPLPLAFSSDHNRMVYFGASSYFFNTASTAYHKAGALVYEITQAMIPKDTGFNLNTSTFSAFIPQLEEMYPNMPMKFRLTAPTAPFLTITPGGISLQPLVDAQAYAILPDSSLAPLFLLSLTGNVSAVINVRSGRIVGSLDVGRIRLSLKDSAVGTFQVRMMQSLMNILTSSTLLPRLNARLDEGFPLPLLDRIQLSNIIVKFHQNFLLLGADVHFQPR
    

Molecular Weight50772.96 Da

Isoelectric Point (pI)9.28

Net Charge (pH 7.0)8.54

Net Charge (pH 7.4) 7.57

Charge Density (pH 7.0) 0.0187

GRAVY Index0.05

Hydrophobic Moment 0.66

Boman Index0.09

Instability Index33.42

Aliphatic Index 101.14

Aromaticity 0.0965

Extinction Coeff. Reduced 33350.00

Extinction Coeff. Oxidized 33475.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0067468 VERIFIED: NO

Provenance & Taxonomy

OrganismDrymodes brunneopygia [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria