Peptide Database

Peptide NameBovine Beta-defensin 11

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC182H288N60O47S8

DescriptionStandard

        NPQSCRWNMGVCIPISCPGNMRQIGTCFGPRVPCCRRW
    

Molecular Weight4325.13 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)4.70

Net Charge (pH 7.4) 4.41

Charge Density (pH 7.0) 0.1237

GRAVY Index-0.27

Hydrophobic Moment 0.43

Boman Index-0.06

Instability Index95.26

Aliphatic Index 46.05

Aromaticity 0.0789

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1713.29

LogP -19.54

H-bond Donors 65.0

H-bond Acceptors 60.0

Rotatable Bonds 131.0

Heavy Atoms 297.0

Ring Count 10.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0172335 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)