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MYP_061254
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
13 amino acids
C66H115N15O18
Standard
Sequence
ILPLVGNLLNDLL
Physicochemical Analysis
1406.71 Da
4.05
-1.24
-1.44
-0.0953
1.46
0.49
0.54
25.80
232.31
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
527.21
-1.44
16.0
17.0
45.0
99.0
1.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0150720 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperAntimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica
RECORD: Rec_0157958 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Non-hemolytic
Escherichia coli
PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
RECORD: Rec_0176944 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Temporin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PaperPubMed PMID: 11835990 PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
RECORD: Rec_0253418 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0282569 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
100 μM
MIC
PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
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