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MYP_061227
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Basic Information
pardaxin-6 (GE-6) (Derived from pardaxin)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C134H217N29O34
Standard
Sequence
GFFALIPKIISSPLFKTLLSAVGSALS
Physicochemical Analysis
2778.33 Da
10.00
1.76
1.55
0.0651
1.26
0.50
0.49
20.11
137.41
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
975.76
-6.31
34.0
36.0
88.0
197.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0362819 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Sheep erythrocytes (50% Hemolysis at 100 microg/ml
100 μg/mL
Hemolysis
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0367675 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Streptococcus pneumoniae BCRC 10794
50 μg/mL
MIC
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0368007 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HeLa
25 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0378560 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
6.25 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0382947 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus
12.5 μg/mL
MIC
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
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