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MYP_061227
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Basic Information
pardaxin-6 (GE-6) (Derived from pardaxin)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
27 amino acids
C134H217N29O34
Standard
Sequence
GFFALIPKIISSPLFKTLLSAVGSALS
Physicochemical Analysis
2778.33 Da
10.00
1.76
1.55
0.0651
1.26
0.50
0.49
20.11
137.41
0.1111
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
975.76
-6.31
34.0
36.0
88.0
197.0
5.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0317972 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Streptococcus pneumoniae
50 μg/mL
MIC
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0321260 VERIFIED: YES
Provenance & Taxonomy
Pardachirus marmoratus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
50 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0325814 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
6.25 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0326999 VERIFIED: YES
Provenance & Taxonomy
Epinephelus nebulosus [Animal]
Epinephelus nebulosus
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Cytotoxic
HT-1080
12.5 μg/mL
Cytotoxicity assay
PaperTruncated antimicrobial peptides from marine organisms retain anticancer activity and antibacterial activity against multidrug-resistant Staphylococcus aureus PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
RECORD: Rec_0362819 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Pardaxin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Sheep erythrocytes
100 μg/mL
Hemolysis
PMID23598079 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23598079/
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